Impact of Conjugation of the Reactive Oxygen Species (ROS)-Generating Catalytic Moiety with Membrane-Active Antimicrobial Peptoids: Promoting Multitarget Mechanism and Enhancing Selectivity-Reference-Cited by-同舟云学术

Impact of Conjugation of the Reactive Oxygen Species (ROS)-Generating Catalytic Moiety with Membrane-Active Antimicrobial Peptoids: Promoting Multitarget Mechanism and Enhancing Selectivity

Published:2024-08-29 Issue:17 Volume:67 Page:15148-15167
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Song Dasom¹,Kim Byeongkwon²,Kim Minsang¹,Lee Jin Kyeong²^ORCID,Choi Jieun¹,Lee Hyeju²,Shin Sujin³,Shin Dongmin¹,Nam Ho Yeon¹^ORCID,Lee Yunho³^ORCID,Lee Seongsoo⁴⁵⁶^ORCID,Kim Yangmee²^ORCID,Seo Jiwon¹^ORCID

Affiliation:

1. Department of Chemistry, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea

2. Department of Bioscience and Biotechnology, Konkuk University, Seoul 05029, Republic of Korea

3. School of Earth Sciences and Environmental Engineering, Gwangju Institute of Science and Technology, Gwangju 61005, Republic of Korea

4. Gwangju Center, Korea Basic Science Institute (KBSI), Gwangju 61751, Republic of Korea

5. Department of Systems Biotechnology, Chung-Ang University, Anseong, Gyeonggi 17546, Republic of Korea

6. Department of Bio-Analysis Science, University of Science & Technology, Daejeon 34113, Republic of Korea

Funder

National Research Foundation of Korea

Ministry of Health and Welfare

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c00775

Reference89 articles.

1. Outer membrane permeability and antibiotic resistance

2. Multiscale modeling of innate immune receptors: Endotoxin recognition and regulation by host defense peptides

3. Combating Sepsis: A Call to Action

4. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock*

5. Antibiotic resistance in sepsis patients: Evaluation and recommendation of antibiotic use