How to Develop and Prove High-Efficiency Selection of Ligands from Oligonucleotide Libraries: A Universal Framework for Aptamers and DNA-Encoded Small-Molecule Ligands-Reference-Cited by-同舟云学术

How to Develop and Prove High-Efficiency Selection of Ligands from Oligonucleotide Libraries: A Universal Framework for Aptamers and DNA-Encoded Small-Molecule Ligands

Published:2021-03-25 Issue:13 Volume:93 Page:5343-5354
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Le An T. H.¹^ORCID,Krylova Svetlana M.¹^ORCID,Beloborodov Stanislav S.¹^ORCID,Wang Tong Y.¹,Hili Ryan¹^ORCID,Johnson Philip E.¹^ORCID,Li Feng²^ORCID,Veedu Rakesh N.³^ORCID,Belyanskaya Svetlana⁴,Krylov Sergey N.¹^ORCID

Affiliation:

1. Department of Chemistry and Centre for Research on Biomolecular Interactions, York University, Toronto, Ontario M3J 1P3, Canada

2. Department of Chemistry and Centre for Biotechnology, Brock University, 1812 Sir Isaac Brock Way, St. Catharines, Ontario L2S 3A1, Canada

3. Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University and Perron Institute for Neurological and Translational Science, Perth 6150, Australia

4. Anagenex, 10 Roessler Rd., Unit N, Woburn, Massachusetts 01801, United States

Funder

Natural Sciences and Engineering Research Council of Canada

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.1c00601

Reference74 articles.

1. Encoded combinatorial chemistry.

2. Hit and lead generation: beyond high-throughput screening