Internal Standard Triggered-Parallel Reaction Monitoring Mass Spectrometry Enables Multiplexed Quantification of Candidate Biomarkers in Plasma

Author:

Kennedy Jacob J.1ORCID,Whiteaker Jeffrey R.1ORCID,Ivey Richard G.1,Burian Aura1,Chowdhury Shrabanti2,Tsai Chia-Feng3ORCID,Liu Tao3ORCID,Lin ChenWei1,Murillo Oscar D.1,Lundeen Rachel A.1,Jones Lisa A.4,Gafken Philip R.4,Longton Gary5,Rodland Karin D.3ORCID,Skates Steven J.6,Landua John7,Wang Pei8,Lewis Michael T.7,Paulovich Amanda G.1ORCID

Affiliation:

1. Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, United States

2. Department of Genetics and Genomic Sciences and Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States

3. Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99352, United States

4. Proteomics and Metabolomics Shared Resources, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, United States

5. Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, United States

6. MGH Biostatistics Center, Harvard Medical School, Boston, Massachusetts 02114, United States

7. Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas 77030, United States

8. Department of Genetics and Genomic Sciences, Mount Sinai Hospital, New York, New York 10065, United States

Funder

National Cancer Institute

Aven Foundation

ORIP

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

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