mD-UPLC-MS/MS: Next Generation of mAb Characterization by Multidimensional Ultraperformance Liquid Chromatography-Mass Spectrometry and Parallel On-Column LysC and Trypsin Digestion-Reference-Cited by-同舟云学术

mD-UPLC-MS/MS: Next Generation of mAb Characterization by Multidimensional Ultraperformance Liquid Chromatography-Mass Spectrometry and Parallel On-Column LysC and Trypsin Digestion

Published:2022-05-12 Issue:23 Volume:94 Page:8136-8145
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Oezipek Saban¹^ORCID,Hoelterhoff Sina¹,Breuer Simon¹,Bell Christian¹,Bathke Anja¹

Affiliation:

1. Pharma Technical Development, F. Hoffmann-La Roche, Grenzacherstrasse 124, 4070 Basel, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.1c04450

Reference22 articles.

1. The pharmacology and therapeutic applications of monoclonal antibodies

2. Assessing monoclonal antibody product quality attribute criticality through clinical studies

3. In vitro and in vivo modifications of recombinant and human IgG antibodies

4. Forced degradation of recombinant monoclonal antibodies: A practical guide

5. Multi-dimensional LC-MS: the next generation characterization of antibody-based therapeutics by unified online bottom-up, middle-up and intact approaches

Cited by 10 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Multidimensional LC-MS with 1D multi-method option and parallel middle-up and bottom-up MS acquisition for in-depth characterization of antibodies;Journal of Chromatography A;2024-07

2. Multi‐dimensional technology – Recent advances and applications for biotherapeutic characterization;Journal of Separation Science;2024-03

3. Sample transformation in online separations: how chemical conversion advances analytical technology;Chemical Communications;2024

4. Comprehensive two-dimensional liquid chromatography;Nature Reviews Methods Primers;2023-11-16

5. Combination of On-Line and Off-Line Two-Dimensional Liquid Chromatography-Mass Spectrometry for Comprehensive Characterization of mAb Charge Variants and Precise Instructions for Rapid Process Development;International Journal of Molecular Sciences;2023-10-14