Top-Down Hydrogen–Deuterium Exchange Analysis of Protein Structures Using Ultraviolet Photodissociation

Author:

Brodie Nicholas I.1,Huguet Romain2,Zhang Terry2,Viner Rosa2,Zabrouskov Vlad2,Pan Jingxi1,Petrotchenko Evgeniy V.1,Borchers Christoph H.1345ORCID

Affiliation:

1. University of Victoria -Genome British Columbia Proteomics Centre, No. 3101-4464 Markham Street, Vancouver Island Technology Park, Victoria, British Columbia V8Z 7X8, Canada

2. Thermo Fisher Scientific, 355 River Oaks Parkway, San Jose, California 95134, United States

3. Department of Biochemistry and Microbiology, University of Victoria, Petch Building, Room 270d, 3800 Finnerty Road, Victoria, British Columbia V8P 5C2, Canada

4. Gerald Bronfman Department of Oncology, Jewish General Hospital, McGill University, 3755 Côte Ste-Catherine Road, Montreal, Quebec H3T 1E2, Canada

5. Proteomics Centre, Segal Cancer Centre, Lady Davis Institute, Jewish General Hospital, McGill University, 3755 Côte Ste-Catherine Road, Montreal, Quebec H3T 1E2, Canada

Funder

Genome British Columbia

McGill University

Genome Canada

Leading Edge Endowment Fund

Natural Sciences and Engineering Research Council of Canada

Warren Y. Soper Charitable Trust

Segal Family Foundation

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

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