Epitope mapping of monoclonal antibodies: a comprehensive comparison of different technologies
Author:
Affiliation:
1. Pharmacokinetics, Merck & Co. Inc, Kenilworth, NJ, USA
2. Research, Aduro Biotech Europe, Oss, The Netherlands
3. Medical, CovalX AG, Zürich, Switzerland
Funder
Merck Sharp & Dohme Corp. LLC, a subsidiary of Merck & Co., Inc
Publisher
Informa UK Limited
Subject
Immunology,Immunology and Allergy
Link
https://www.tandfonline.com/doi/pdf/10.1080/19420862.2023.2285285
Reference35 articles.
1. The Increasingly Human and Profitable Monoclonal Antibody Market
2. FDA approves 100th monoclonal antibody product
3. Characterization of MK-4166, a Clinical Agonistic Antibody That Targets Human GITR and Inhibits the Generation and Suppressive Effects of T Regulatory Cells
4. HuMab-7D8, a monoclonal antibody directed against the membrane-proximal small loop epitope of CD20 can effectively eliminate CD20low expressing tumor cells that resist rituximab-mediated lysis
5. Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus
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