Standard-Free Bioanalytical Approach for Absolute Quantitation of Drug Metabolites Utilizing Biosynthesis of Reciprocal Radio and Stable Isotopologues and Its Application
Author:
Affiliation:
1. Department of Pharmacokinetics Dynamics & Metabolism, Janssen Research & Development, Johnson & Johnson, Welsh & McKean Roads, Spring House, Pennsylvania 19477, United States
Publisher
American Chemical Society (ACS)
Subject
Analytical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.7b01830
Reference30 articles.
1. The early estimation of circulating drug metabolites in humans
2. LC-MS Development Strategies for Quantitative Bioanalysis
3. Unger, S.; Weng, N.InHandbook of LC-MS Bioanalysis;Li, W.; Zhang, J.; Tse, F. L. S., Eds.Wiley:New York, 2013; pp185–204.
Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Metabolism and disposition of JNJ-10450232 (NTM-006) in rats, dogs, monkeys and humans;Regulatory Toxicology and Pharmacology;2023-03
2. Elemental detection of fluorochemicals by nanospray-induced chemical ionization in afterglow of an inductively coupled plasma;Journal of Analytical Atomic Spectrometry;2022
3. Bifunctionalized isotopologs as calibrants for standard‐free quantitation of drug metabolites in plasma by liquid chromatography coupled with radiometry and mass spectrometry;Biomedical Chromatography;2021-10-03
4. Evaluation of the uncertainty of a quantitative approach to drug metabolites in the absence of authentic standards;Bioanalysis;2020-01
5. Bioanalysis of small and large molecule drugs, metabolites, and biomarkers by LC-MS;Identification and Quantification of Drugs, Metabolites, Drug Metabolizing Enzymes, and Transporters;2020
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3