Label-Free Quantitative Thermal Proteome Profiling Reveals Target Transcription Factors with Activities Modulated by MC3R Signaling
Author:
Affiliation:
1. Department of Pharmaceutical Biosciences, Uppsala University, 751 24 Uppsala, Sweden
2. Science for Life Laboratory, Spatial Mass Spectrometry, Uppsala University, 751 24 Uppsala, Sweden
Funder
Science for Life Laboratory
Vetenskapsr?det
?ke Wiberg Stiftelse
Stiftelsen f?r Strategisk Forskning
Publisher
American Chemical Society (ACS)
Subject
Analytical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.3c03643
Reference34 articles.
1. The cellular thermal shift assay for evaluating drug target interactions in cells
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3. Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat
4. Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP
5. Thermal proteome profiling for interrogating protein interactions
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