Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry-Reference-Cited by-同舟云学术

Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry

Published:2015-09-17 Issue:10 Volume:10 Page:1567-1593
ISSN:1754-2189
Container-title:Nature Protocols
language:en
Short-container-title:Nat Protoc

Author:

Franken Holger,Mathieson Toby,Childs Dorothee,Sweetman Gavain M A,Werner Thilo,Tögel Ina,Doce Carola,Gade Stephan,Bantscheff Marcus^ORCID,Drewes Gerard,Reinhard Friedrich B M,Huber Wolfgang^ORCID,Savitski Mikhail M

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology

Link

http://www.nature.com/articles/nprot.2015.101.pdf

Reference47 articles.

1. Schenone, M., Dancik, V., Wagner, B.K. & Clemons, P.A. Target identification and mechanism of action in chemical biology and drug discovery. Nat. Chem. Biol. 9, 232–240 (2013).

2. Martinez Molina, D. et al. Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay. Science 341, 84–87 (2013).

3. Jafari, R. et al. The cellular thermal shift assay for evaluating drug target interactions in cells. Nat. Protoc. 9, 2100–2122 (2014).

4. Linderstrøm-Lang, K. & Schellman, J.A. Protein structure and enzyme activity. Enzymes 1, 443–510 (1959).

5. Pantoliano, M.W. et al. High-density miniaturized thermal shift assays as a general strategy for drug discovery. J. Biomol. Screen. 6, 429–440 (2001).

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