New Design of an Activity Assay Suitable for High-Throughput Screening of Substrates and Inhibitors of the Mitochondrial Amidoxime Reducing Component (mARC)-Reference-Cited by-同舟云学术

New Design of an Activity Assay Suitable for High-Throughput Screening of Substrates and Inhibitors of the Mitochondrial Amidoxime Reducing Component (mARC)

Published:2023-08-07 Issue:33 Volume:95 Page:12452-12458
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Klopp Cathrin¹²,Struwe Michel A.¹²,Plieth Christoph³,Clement Bernd¹^ORCID,Scheidig Axel J.²^ORCID

Affiliation:

1. Pharmaceutical Institute − Medicinal Chemistry, Kiel University, Gutenbergstraße 76, 24118 Kiel, Germany

2. Zoological Institute − Structural Biology, Kiel University, Am Botanischen Garten 9, 24118 Kiel, Germany

3. Centre for Biochemistry and Molecular Biology, Kiel University, Am Botanischen Garten 9, 24118 Kiel, Germany

Funder

Studienstiftung des Deutschen Volkes

Joachim Herz Stiftung

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.3c02109

Reference33 articles.

1. Biotransformation: Impact and Application of Metabolism in Drug Discovery

2. Glossary of terms used in medicinal chemistry (IUPAC Recommendations 1998)

3. Phang-Lyn, S.; Llerena, V. A., Eds.; StatPearls [Internet]; StatPearls Publishing, 2022.

4. The Role of Biotransformation in Drug Discovery and Development

5. Cytochrome P450-Activated Prodrugs: Targeted Drug Delivery

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