Biotransformation: Impact and Application of Metabolism in Drug Discovery
Author:
Affiliation:
1. Hypha Discovery Ltd., 154B Brook Drive, Milton Park, Abingdon, Oxfordshire OX14 4SD, U.K.
2. Incyte Corporation, 1801 Augustine Cut-off, Wilmington, Delaware 19803, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.0c00202
Reference87 articles.
1. Effective Application of Metabolite Profiling in Drug Design and Discovery
2. Clearance in Drug Design
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4. Late-occurring and Long-circulating Metabolites of GABAAα2,3 Receptor Modulator AZD7325 Involving Metabolic Cyclization and Aromatization: Relevance to MIST Analysis and Application for Patient Compliance
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