Targeted Bottom-up Characterization of Recombinant Monoclonal Antibodies by Multidimensional LC/MS
Author:
Affiliation:
1. Protein Analytical Chemistry, Genentech, 1 DNA Way, South San Francisco, California 94080, United States
2. School of Pharmaceutical Sciences, University of Geneva, CMU, Rue Michel-Servet, 1, 1206 Geneva, Switzerland
Publisher
American Chemical Society (ACS)
Subject
Analytical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.0c02780
Reference23 articles.
1. Determination of critical quality attributes for monoclonal antibodies using quality by design principles
2. Selective Oxidation of Methionine and Tryptophan Residues in a Therapeutic IgG1 Molecule
3. Identification of isomerization and racemization of aspartate in the Asp–Asp motifs of a therapeutic protein
4. Characterization of Therapeutic Antibodies and Related Products
5. Fc glycans of therapeutic antibodies as critical quality attributes
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