Fast and Automated Characterization of Monoclonal Antibody Minor Variants from Cell Cultures by Combined Protein-A and Multidimensional LC/MS Methodologies
Author:
Affiliation:
1. Protein Analytical Chemistry, Genentech, 1 DNA Way, South San Francisco, California 94080, United States
2. School of Pharmaceutical Sciences, University of Geneva, CMU - Rue Michel-Servet, 1, 1206 Geneva, Switzerland
Publisher
American Chemical Society (ACS)
Subject
Analytical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.0c01250
Reference33 articles.
1. Determination of critical quality attributes for monoclonal antibodies using quality by design principles
2. Advances in recombinant antibody manufacturing
3. Glycosylation as a strategy to improve antibody-based therapeutics
4. Characterization of the influence of cultivation parameters on extracellular modifications of antibodies during fermentation
Cited by 30 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Sample transformation in online separations: how chemical conversion advances analytical technology;Chemical Communications;2024
2. Online multimethod platform for comprehensive characterization of monoclonal antibodies in cell culture fluid from a single sample injection - Intact protein workflow;Analytica Chimica Acta;2024-01
3. Automated Online-Sampling Multidimensional Liquid Chromatography with Feedback-Control Capability as a Framework for Real-Time Monitoring of mAb Critical Quality Attributes in Multiple Bioreactors;Analytical Chemistry;2023-11-28
4. Recent trends in two-dimensional liquid chromatography;TrAC Trends in Analytical Chemistry;2023-09
5. What is the role of current mass spectrometry in pharmaceutical analysis?;Mass Spectrometry Reviews;2023-07-28
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3