Automated Online-Sampling Multidimensional Liquid Chromatography with Feedback-Control Capability as a Framework for Real-Time Monitoring of mAb Critical Quality Attributes in Multiple Bioreactors-Reference-Cited by-同舟云学术

Automated Online-Sampling Multidimensional Liquid Chromatography with Feedback-Control Capability as a Framework for Real-Time Monitoring of mAb Critical Quality Attributes in Multiple Bioreactors

Published:2023-11-28 Issue:49 Volume:95 Page:18130-18138
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Dunn Zachary D.¹^ORCID,Bohman Patrick²,Quinteros Alexis³,Sauerborn Brian⁴,Milman Felix⁴,Patel Misaal³,Kargupta Roli³,Wu Suyang³,Hornshaw Martin²,Barrientos Rodell¹,Bones Jonathan⁵⁶^ORCID,Tayi Venkata S.³,Abaroa Nicholas⁴,Patel Bhumit¹^ORCID,Appiah-Amponsah Emmanuel¹,Regalado Erik L.¹^ORCID

Affiliation:

1. Analytical Research and Development, MRL, Merck & Co., Inc., Rahway, New Jersey 07065, United States

2. Thermo Fisher Scientific, 168 Third Avenue, Waltham, Massachusetts 02451, United States

3. Process Research and Development, MRL, Merck & Co., Inc., Rahway, New Jersey 07065, United States

4. Engineering, MRL, Merck & Co., Inc., Rahway, New Jersey 07065, United States

5. The National Institute for Bioprocessing Research and Training, Foster Avenue, Mount Merrion, Blackrock, Co., Dublin A94 X099, Ireland

6. School of Chemical and Bioprocess Engineering, University College Dublin, Belfield, Dublin 4 D04 V1W8, Ireland

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.3c03528

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