When Good Intentions Go Awry: Modification of a Recombinant Monoclonal Antibody in Chemically Defined Cell Culture by Xylosone, an Oxidative Product of Ascorbic Acid-Reference-Cited by-同舟云学术

When Good Intentions Go Awry: Modification of a Recombinant Monoclonal Antibody in Chemically Defined Cell Culture by Xylosone, an Oxidative Product of Ascorbic Acid

Published:2015-07-21 Issue:15 Volume:87 Page:7529-7534
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Chumsae Chris¹²,Hossler Patrick³,Raharimampionona Haly¹,Zhou Yu¹,McDermott Sean³,Racicot Chris³,Radziejewski Czeslaw¹,Zhou Zhaohui Sunny²

Affiliation:

1. Protein Analytics, Process Sciences Department, AbbVie Bioresearch Center, Worcester, Massachusetts 01605, United States

2. Barnett Institute of Chemical and Biological Analysis, Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States

3. Cell Culture, Process Sciences Department, AbbVie Bioresearch Center, Worcester, Massachusetts 01605, United States

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.5b00801

Reference58 articles.

1. Mass spectrometry of oligosaccharides

2. Mass spectrometric analysis of proteins