SAR and pH Stability of Cyano-Substituted Epothilones-Reference-Cited by-同舟云学术

SAR and pH Stability of Cyano-Substituted Epothilones

Published:2002-10-01 Issue:22 Volume:4 Page:3815-3818
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Regueiro-Ren Alicia¹,Leavitt Kenneth¹,Kim Soong-Hoon¹,Höfle Gerhard¹,Kiffe Michael¹,Gougoutas Jack Z.¹,DiMarco John D.¹,Lee Francis Y. F.¹,Fairchild Craig R.¹,Long Byron H.¹,Vite Gregory D.¹

Affiliation:

1. Divisions of Discovery Chemistry, Oncology Drug Discovery and Pharmaceutical Development, The Bristol-Myers Squibb Pharmaceutical Research Institute, P.O. Box 4000, Princeton, New Jersey 08543-4000, and Gesellschaft für Biotechnologische Forschung mbH, Abt. Naturstoffchemie, Mascheroder Weg 1, D-38124 Braunschweig, Germany

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol026589j

Reference27 articles.

1. The Epothilones, Eleutherobins, and Related Types of Molecules

2. Microtubule-stabilizing agents: a growing class of important anticancer drugs

3. Highly Efficient Semisynthesis of Biologically Active Epothilone Derivatives

4. Epothilones and their analogues - a new class of promising microtubule inhibitors

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