Development of a Practical and Scalable Synthesis of a Potent Selective Dual Antagonist for 5-HT2B and 5-HT7 Receptors-Reference-Cited by-同舟云学术

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Development of a Practical and Scalable Synthesis of a Potent Selective Dual Antagonist for 5-HT2B and 5-HT7 Receptors

Published:2012-04-05 Issue:4 Volume:16 Page:654-663
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Yoshida Shinya¹,Kasai Makoto¹,Kimura Takenori²,Akiba Takahiro¹,Takahashi Takumi¹,Sakamoto Shuichi³

Affiliation:

1. Process Chemistry Laboratories, Astellas Pharma Inc., 160-2 Akahama, Takahagi-shi, Ibaraki 318-0001, Japan

2. Astellas Research Technologies Co., Ltd., 21 Miyukigaoka, Tsukuba-shi, Ibaraki 305-8585, Japan

3. Astellas Pharma Europe B.V., Elisabethhof 19, 2353 EW Leiderdorp, The Netherlands

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op200380z

Reference24 articles.

1. Route Scouting and Process Development of Lu AA26778

2. One-step annulation. A convenient method for the preparation of diols, spirolactones, and spiroethers from lactones

3. One-step spiroannulation. Synthesis of spiro .gamma.- and .delta.-lactones

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