(2,2‘:6‘,2‘ ‘-Terpyridine)platinum(II) Complexes Are Irreversible Inhibitors of Trypanosoma cruzi Trypanothione Reductase But Not of Human Glutathione Reductase-Reference-Cited by-同舟云学术

(2,2‘:6‘,2‘ ‘-Terpyridine)platinum(II) Complexes Are Irreversible Inhibitors of Trypanosoma cruzi Trypanothione Reductase But Not of Human Glutathione Reductase

Published:2000-11-23 Issue:25 Volume:43 Page:4812-4821
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bonse Susanne¹,Richards Jonathan M.¹,Ross Steven A.¹,Lowe Gordon¹,Krauth-Siegel R. Luise¹

Affiliation:

1. Biochemie-Zentrum Heidelberg, Heidelberg University, Im Neuenheimer Feld 328, D-69120 Heidelberg, Germany, and Dyson Perrins Laboratory, Oxford University, South Parks Road, Oxford OX1 3QY, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm000219o

Reference50 articles.

1. Trypanothione: A Novel Bis(glutathionyl)spermidine Cofactor for Glutathione Reductase in Trypanosomatids

2. Mixed Disulfide with Glutathione as an Intermediate in the Reaction Catalyzed by Glutathione Reductase from Yeast and as a Major Form of the Enzyme in the Cell

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