Synthesis and Biological Evaluation of α- and β-6-Amido Derivatives of 17-Cyclopropylmethyl-3, 14β-dihydroxy-4, 5α-epoxymorphinan: Potential Alcohol-Cessation Agents-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of α- and β-6-Amido Derivatives of 17-Cyclopropylmethyl-3, 14β-dihydroxy-4, 5α-epoxymorphinan: Potential Alcohol-Cessation Agents

Published:2008-02-26 Issue:6 Volume:51 Page:1913-1924
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ghirmai Senait¹,Azar Marc R.¹,Polgar Wilma E.¹,Berzetei-Gurske Ilona¹,Cashman John R.¹

Affiliation:

1. Human BioMolecular Research Institute, 5310 Eastgate Mall, San Diego, California 92121-2804, Behavioral Pharma, Inc., 505 Coast Boulevard South, Suite 210, La Jolla, California 92037, and SRI International, 333 Ravenswood Avenue, Menlo Park, California 94025

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm701060e

Reference40 articles.

1. Enhanced Sensitivity of Pituitary βEndorphin to Ethanol in Subjects at High Risk of Alcoholism

2. A systematic review of the effectiveness of naltrexone in the maintenance treatment of opioid and alcohol dependence

3. The Role of Opioid Receptor Subtypes in the Development of Behavioral Sensitization to Ethanol

4. Efficacy and safety of naltrexone and acamprosate in the treatment of alcohol dependence: a systematic review

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design, Synthesis, and Biological Evaluation of NAP Isosteres: A Switch from Peripheral to Central Nervous System Acting Mu-Opioid Receptor Antagonists;Journal of Medicinal Chemistry;2022-03-08

2. Construction of a Virtual Opioid Bioprofile: A Data-Driven QSAR Modeling Study to Identify New Analgesic Opioids;ACS Sustainable Chemistry & Engineering;2021-03-04

3. Neuroendocrine effects of naltrexone versus nalmefene in humans;Human Psychopharmacology: Clinical and Experimental;2020-02-12

4. Alcohol dependence and opioid receptor —Pharmacological profile of nalmefene—;Folia Pharmacologica Japonica;2020

5. Pharmacological profile and clinical findings of nalmefene (Selincro^®) for reducing alcohol consumption in patients with alcohol dependence;Folia Pharmacologica Japonica;2020