Design, Synthesis, and Biological Evaluation of NAP Isosteres: A Switch from Peripheral to Central Nervous System Acting Mu-Opioid Receptor Antagonists-Reference-Cited by-同舟云学术

Design, Synthesis, and Biological Evaluation of NAP Isosteres: A Switch from Peripheral to Central Nervous System Acting Mu-Opioid Receptor Antagonists

Published:2022-03-08 Issue:6 Volume:65 Page:5095-5112
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pagare Piyusha P.¹^ORCID,Li Mengchu¹,Zheng Yi¹,Kulkarni Abhishek S.¹,Obeng Samuel¹,Huang Boshi¹,Ruiz Christian¹^ORCID,Gillespie James C.²,Mendez Rolando E.²,Stevens David L.²,Poklis Justin L.²,Halquist Matthew S.³,Dewey William L.²,Selley Dana E.²,Zhang Yan¹^ORCID

Affiliation:

1. Department of Medicinal Chemistry, Virginia Commonwealth University, 800 E. Leigh Street, Richmond, Virginia 23219, United States

2. Department of Pharmacology and Toxicology, Virginia Commonwealth University, 410 North 12th Street, Richmond, Virginia 23298, United States

3. Department of Pharmaceutics, Virginia Commonwealth University, 410 North 12th Street, Richmond, Virginia 23298, United States

Funder

National Institute on Drug Abuse

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00087

Reference75 articles.

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