Marineosins A and B, Cytotoxic Spiroaminals from a Marine-Derived Actinomycete
Author:
Affiliation:
1. Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California−San Diego, La Jolla, California 92093-0204
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol8020644
Reference14 articles.
1. Developing a new resource for drug discovery: marine actinomycete bacteria
2. Salinispora arenicola gen. nov., sp. nov. and Salinispora tropica sp. nov., obligate marine actinomycetes belonging to the family Micromonosporaceae
3. Bioactive Microbial Metabolites
4. Phylogenetic Diversity of Gram-Positive Bacteria Cultured from Marine Sediments
5. Marineosin A (1): colorless oil; [α]D−101.7 (c0.06, MeOH); UV (MeOH) λmax(log ε) 285 nm (4.06), 227 nm (3.88); IR νmax(KBr) 2925, 2856, 1610, 1508, 1435, 1261, 763 cm−1; NMR spectral data, see Table1andSI; HREIMS [M]+m/z409.2726 (calcd for C25H35N3O2, 409.2729).
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