Design of Multi-Binding-Site Inhibitors, Ligand Efficiency, and Consensus Screening of Avian Influenza H5N1 Wild-Type Neuraminidase and of the Oseltamivir-Resistant H274Y Variant-Reference-Cited by-同舟云学术

Design of Multi-Binding-Site Inhibitors, Ligand Efficiency, and Consensus Screening of Avian Influenza H5N1 Wild-Type Neuraminidase and of the Oseltamivir-Resistant H274Y Variant

Published:2008-10-11 Issue:10 Volume:48 Page:2074-2080
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

García-Sosa Alfonso T.¹,Sild Sulev¹,Maran Uko¹

Affiliation:

1. Institute of Chemistry, University of Tartu, Jakobi 2-319, Tartu 51014, Estonia

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ci800242z

Reference36 articles.

1. World Health Organization. Cumulative Number of Confirmed Human Cases of Avian Influenza A/(H5N1) Reported to WHO, 18 Mar 2008, 2008.

2. World Health Organization. Influenza A (H5N1) in Hong Kong Special Administrative Region of China, 19 Feb 2003, 2003.

3. Influenza Neuraminidase Inhibitors Possessing a Novel Hydrophobic Interaction in the Enzyme Active Site: Design, Synthesis, and Structural Analysis of Carbocyclic Sialic Acid Analogues with Potent Anti-Influenza Activity

4. Rational design of potent sialidase-based inhibitors of influenza virus replication

5. Selection of Influenza Virus Mutants in Experimentally Infected Volunteers Treated with Oseltamivir

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