A Bivalent Ligand (KDN-21) Reveals Spinal δ and κ Opioid Receptors Are Organized as Heterodimers That Give Rise to δ1 and κ2 Phenotypes. Selective Targeting of δ−κ Heterodimers-Reference-Cited by-同舟云学术

A Bivalent Ligand (KDN-21) Reveals Spinal δ and κ Opioid Receptors Are Organized as Heterodimers That Give Rise to δ1 and κ2 Phenotypes. Selective Targeting of δ−κ Heterodimers

Published:2004-05-08 Issue:12 Volume:47 Page:2969-2972
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bhushan Rashmi G.¹,Sharma Shiv K.¹,Xie Zhihua¹,Daniels David J.¹,Portoghese Philip S.¹

Affiliation:

1. Department of Medicinal Chemistry, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota 55455

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0342358

Reference23 articles.

1. Dimerization: An Emerging Concept for G Protein–Coupled Receptor Ontogeny and Function

2. Oligomerization of opioid receptors: generation of novel signaling units

3. Identity of the putative δ1-opioid receptor as a δ–κ heteromer in the mouse spinal cord

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