Ancistrosecolines A–F, Unprecedented seco-Naphthylisoquinoline Alkaloids from the Roots of Ancistrocladus abbreviatus, with Apoptosis-Inducing Potential against HeLa Cancer Cells

Author:

Fayez Shaimaa12,Bruhn Torsten3ORCID,Feineis Doris1,Assi Laurent Aké4,Awale Suresh5ORCID,Bringmann Gerhard1ORCID

Affiliation:

1. Institute of Organic Chemistry, University of Würzburg, Am Hubland, D-97074 Würzburg, Germany

2. Department of Pharmacognosy, Faculty of Pharmacy, Ain-Shams University, Organization of African Unity Street 1, 11566 Cairo, Egypt

3. Federal Institute for Risk Assessment, Max-Dohrn-Straße 8-10, D-10589 Berlin, Germany

4. Centre National de Floristique, Conservatoire et Jardin Botaniques, Université d’Abidjan, Abidjan 08, Ivory Coast

5. Division of Natural Drug Discovery, Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan

Funder

Deutscher Akademischer Austausch Dienst Kairo

Deutsche Forschungsgemeinschaft

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Reference59 articles.

1. Dimeric naphthylisoquinoline alkaloids: polyketide-derived axially chiral bioactive quateraryls

2. Naphthylisoquinoline alkaloids potential drug leads

3. Bringmann, G.; Pokorny, F. In The Alkaloids; Cordell, G. A., Ed. Academic Press: New York, 1995; Vol. 46, Chapter 4, pp 127–271.

4. Bringmann, G.; Günther, C.; Ochse, M.; Schupp, O.; Tasler, S. In Progress in the Chemistry of Organic Natural Products; Herz, W.; Falk, H.; Kirby, G. W.; Moore, R. E., Eds. Springer: Wien, 2001; Vol. 82, pp 111–123.

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