11-Aminostrychnine and N-(Strychnine-11-yl)propionamide: Synthesis, Configuration, and Pharmacological Evaluation at Glycine Receptors-Reference-Cited by-同舟云学术

11-Aminostrychnine and N-(Strychnine-11-yl)propionamide: Synthesis, Configuration, and Pharmacological Evaluation at Glycine Receptors

Published:2019-08-06 Issue:8 Volume:82 Page:2332-2336
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Zlotos Darius P.¹^ORCID,Mohsen Amal M. Y.¹,Mandour Yasmine M.¹,Marzouk Mohamed A.¹,Breitinger Ulrike¹,Villmann Carmen²,Breitinger Hans-Georg¹^ORCID,Sotriffer Christoph³^ORCID,Jensen Anders A.⁴,Holzgrabe Ulrike³^ORCID

Affiliation:

1. Faculty of Pharmacy and Biotechnology, The German University in Cairo, New Cairo City, 11835 Cairo, Egypt

2. Institute of Clinical Neurobiology, University of Würzburg, 97078 Würzburg, Germany

3. Institute of Pharmacy and Food Chemistry, University of Würzburg, 97074 Würzburg, Germany

4. Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100 Copenhagen, Denmark

Funder

Bundesministerium f?r Bildung und Forschung

Deutscher Akademischer Austauschdienst

Novo Nordisk Fonden

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.9b00180

Reference24 articles.

1. Molecular Structure and Function of the Glycine Receptor Chloride Channel

2. Modulation of glycine receptor function: a novel approach for therapeutic intervention at inhibitory synapses?

3. Conserved quaternary structure of ligand-gated ion channels: the postsynaptic glycine receptor is a pentamer.

4. Native glycine receptor subtypes and their physiological roles

5. Functional characterisation of the human α1 glycine receptor in a fluorescence-based membrane potential assay

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