Psiguadiols A–J, Rearranged Meroterpenoids as Potent PTP1B Inhibitors from Psidium guajava-Reference-Cited by-同舟云学术

Psiguadiols A–J, Rearranged Meroterpenoids as Potent PTP1B Inhibitors from Psidium guajava

Published:2019-11-18 Issue:12 Volume:82 Page:3267-3278
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Hou Ji-Qin¹,Fan Chun-Lin²,Pei Xin¹,Zhang Pei-Lin¹,Deng Fan¹,Jiang Wan-Qiang¹,Wang Guo-Cai²,Zhang Xiao-Qi²,Ye Wen-Cai²^ORCID,Wang Hao¹^ORCID

Affiliation:

1. State Key Laboratory of Natural Medicines, Department of TCMs Pharmaceuticals, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, People’s Republic of China

2. Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou 510632, People’s Republic of China

Funder

Ministry of Science and Technology of the People's Republic of China

China Postdoctoral Science Foundation

Natural Science Foundation of Jiangsu Province

National Natural Science Foundation of China

Double First-rate Discipline Innovation Team

Double First-rate Discipline Innovation Tea

Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.9b00333

Reference25 articles.

1. PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice

2. Osmotic Loading of Neutralizing Antibodies Demonstrates a Role for Protein-tyrosine Phosphatase 1B in Negative Regulation of the Insulin Action Pathway

3. Unraveling the Causes of Diabetes

4. PTP1B as a drug target: recent developments in PTP1B inhibitor discovery

5. Two New Triterpenoids from the Fresh Leaves ofPsidium guajava

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