Kendomycin Cytotoxicity against Bacterial, Fungal, and Mammalian Cells Is Due to Cation Chelation
Author:
Affiliation:
1. Institute of Biotechnology, University of Helsinki, Helsinki, 00014, Finland
2. Novartis Institutes for BioMedical Research, 4056 Basel, Switzerland
Funder
Academy of Finland
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry
Link
http://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.9b00826
Reference34 articles.
1. Diversity of nonribosomal peptide synthetase and polyketide synthase genes in the genus Actinoplanes found in Mongolia
2. Evidence for the Mode of Action of the Highly CytotoxicStreptomyces Polyketide Kendomycin
3. Total Synthesis of Kendomycin: A Macro−C−Glycosidation Approach
4. A Type I/Type III Polyketide Synthase Hybrid Biosynthetic Pathway for the Structurally UniqueansaCompound Kendomycin
5. Interactions of the natural product kendomycin and the 20S proteasome
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