Diosgenin Derivatives as Potential Antitumor Agents: Synthesis, Cytotoxicity, and Mechanism of Action

Author:

Yin Hong1,Zhang Min-Jie1,An Ren-Feng1,Zhou Jing1,Liu Wei2,Morris-Natschke Susan L.3,Cheng Yung-Yi3,Lee Kuo-Hsiung34ORCID,Huang Xue-Feng1ORCID

Affiliation:

1. Department of Natural Medicinal Chemistry, School of Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, People’s Republic of China

2. Department of Pharmacology, Nanjing Medical University, Nanjing 210029, People’s Republic of China

3. Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599, United States

4. Chinese Medicine Research and Development Center, China Medical University and Hospital, Taichung 40402, Taiwan

Funder

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

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