Top-down Targeted Metabolomics Reveals a Sulfur-Containing Metabolite with Inhibitory Activity against Angiotensin-Converting Enzyme in Asparagus officinalis-Reference-Cited by-同舟云学术

Top-down Targeted Metabolomics Reveals a Sulfur-Containing Metabolite with Inhibitory Activity against Angiotensin-Converting Enzyme in Asparagus officinalis

Published:2015-04-29 Issue:5 Volume:78 Page:1179-1183
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Nakabayashi Ryo¹,Yang Zhigang¹,Nishizawa Tomoko¹,Mori Tetsuya¹,Saito Kazuki¹²

Affiliation:

1. RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan

2. Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8675, Japan

Funder

Japan Science and Technology Agency

RIKEN

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.5b00092

Reference23 articles.

1. Drugs targeting the renin–angiotensin–aldosterone system

2. Ace revisited: A new target for structure-based drug design

3. Haj-Yehia, A. I.; Khan, M. A.; Qadri, B. A.Eur. Pat. 20,030,777,134, 2005.

4. Nicotianamine Contents among Vegetables and their Inhibitory Activity of Angiotensin-I Converting Enzyme

5. Green Asparagus (Asparagus officinalis) Prevented Hypertension by an Inhibitory Effect on Angiotensin-Converting Enzyme Activity in the Kidney of Spontaneously Hypertensive Rats

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