Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases-Reference-Cited by-同舟云学术

Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases

Published:2023-10-16 Issue:10 Volume:86 Page:2283-2293
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Du Lin¹^ORCID,Wilson Brice A. P.¹^ORCID,Li Ning²,Shah Rohan¹,Dalilian Masoumeh¹³,Wang Dongdong¹^ORCID,Smith Emily A.¹³,Wamiru Antony¹³,Goncharova Ekaterina I.¹³,Zhang Ping²,O’Keefe Barry R.¹⁴^ORCID

Affiliation:

1. Molecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States

2. Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States

3. Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702, United States

4. Natural Products Branch, Development Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Frederick, Maryland 21702, United States

Funder

National Cancer Institute

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.3c00394

Reference89 articles.

1. Trends in kinase drug discovery: targets, indications and inhibitor design

2. A comprehensive map of molecular drug targets

3. Properties of FDA-approved small molecule protein kinase inhibitors: A 2022 update

4. Kinase drug discovery 20 years after imatinib: progress and future directions

5. The Landscape of Atypical and Eukaryotic Protein Kinases

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