Acroamine A, a 2-Amino Adenine Alkaloid from the Marine Soft Coral <i>Acrozoanthus australiae</i> and Its Semisynthetic Derivatives That Inhibit cAMP-Dependent Protein Kinase A Catalytic Subunit Alpha-Reference-Cited by-同舟云学术

Acroamine A, a 2-Amino Adenine Alkaloid from the Marine Soft Coral Acrozoanthus australiae and Its Semisynthetic Derivatives That Inhibit cAMP-Dependent Protein Kinase A Catalytic Subunit Alpha

Published:2024-08-14 Issue:8 Volume:87 Page:2014-2020
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Senadeera Sarath P. D.¹,Wang Dongdong¹^ORCID,Wilson Brice A. P.¹^ORCID,Smith Emily A.¹,Wamiru Antony¹²,Martinez Fiesco Juliana A.³,Du Lin¹^ORCID,Zhang Ping³,O’Keefe Barry R.¹⁴^ORCID,Beutler John A.¹^ORCID

Affiliation:

1. Molecular Targets Program, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702-1201, United States

2. Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702, United States

3. Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702-1201, United States

4. Natural Products Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Frederick, Maryland 21702-1201, United States

Funder

National Cancer Institute

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.4c00477

Reference25 articles.

1. cAMP Signaling in Cancer: A PKA-CREB and EPAC-Centric Approach

2. Fibrolamellar hepatocellular carcinoma: Exploring molecular mechanisms and differentiation pathways to better understand disease outcomes and prognosis

3. Biochemical Discovery, Intracellular Evaluation, and Crystallographic Characterization of Synthetic and Natural Product Adenosine 3′,5′-Cyclic Monophosphate-Dependent Protein Kinase A (PKA) Inhibitors

4. Marine microorganisms as a promising and sustainable source of bioactive molecules

5. Marine natural products