Design and Implementation of an Efficient Synthetic Approach to Pyranosylated Indolocarbazoles: Total Synthesis of (+)-RK286c, (+)-MLR-52, (+)-Staurosporine, and (−)-TAN-1030a-Reference-Cited by-同舟云学术

Design and Implementation of an Efficient Synthetic Approach to Pyranosylated Indolocarbazoles: Total Synthesis of (+)-RK286c, (+)-MLR-52, (+)-Staurosporine, and (−)-TAN-1030a

Published:1997-10-01 Issue:41 Volume:119 Page:9652-9661
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Wood John L.¹,Stoltz Brian M.¹,Goodman Steven N.¹,Onwueme Kenolisa¹

Affiliation:

1. Contribution from the Sterling Chemistry Laboratory, Department of Chemistry, Yale University, New Haven, Connecticut 06520-8107

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja971304x

Reference16 articles.

1. Total Synthesis of (+)-RK-286c, (+)-MLR-52, (+)-Staurosporine, and (+)-K252a

2. A new alkaloid AM-2282 of Streptomyces origin taxonomy, fermentation, isolation and preliminary characterization.

3. Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

4. A new inhibitor of protein kinase C, RK-286C (4'-demethylamino-4'-hydroxystaurosporine) II. Isolation, physico-chemical properties and structure.

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