Structural Determinants of Opioid Activity in the Orvinols and Related Structures: Ethers of Orvinol and Isoorvinol-Reference-Cited by-同舟云学术

Structural Determinants of Opioid Activity in the Orvinols and Related Structures: Ethers of Orvinol and Isoorvinol

Published:2000-04-14 Issue:9 Volume:43 Page:1852-1857
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Coop Andrew¹,Norton Claire L.¹,Berzetei-Gurske Ilona¹,Burnside Jackie¹,Toll Lawrence¹,Husbands Stephen M.¹,Lewis John W.¹

Affiliation:

1. School of Chemistry, Cantock's Close, University of Bristol, Bristol BS8 1TS, England, and SRI, Menlo Park, California

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm990951r

Reference16 articles.

1. Narcotic Analgesics and Antagonists

2. Buprenorphine.Combating Drug Abuse with a unique Opioid; Cowan, A., Lewis, J. W., Eds.; Wiley-Liss: New York, 1995; pp 326.

3. Bentley, K. W.; Lewis, J. W. The Relationship between Structure and Activity in the 6,14-endoethenotetrahydrothebaine Series of Analgesics. Part II. Reported toCommittee on Problems of Drug Dependence, 1968, Appendix 22, pp 5454−5461.

Cited by 14 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. C(21)-fluorinated thevinol scaffold for opioid ligands. 21,21,21-Trifluoro-6-O-nororvinols: Design, synthesis and analgesic activity;European Journal of Medicinal Chemistry;2023-04

2. Control of the diastereoselectivity at C(20) in the formation of C(21)-fluorinated thevinols;Organic & Biomolecular Chemistry;2023

3. Diels–Alder Adducts of Morphinan-6,8-Dienes and Their Transformations;Molecules;2022-04-30

4. Selectively Promiscuous Opioid Ligands: Discovery of High Affinity/Low Efficacy Opioid Ligands with Substantial Nociceptin Opioid Peptide Receptor Affinity;Journal of Medicinal Chemistry;2014-05-09

5. Synthesis and evaluation of κ-opioid receptor agonistic activity and antinociceptive effect of novel morphine analogues, 7α-phenyl-6α,14α-endo-etheno-tetrahydrothebaine with substituted o-, m- and p-amino group;Medicinal Chemistry Research;2010-11-17