Synthesis of Pluraflavin A “Aglycone”-Reference-Cited by-同舟云学术

Synthesis of Pluraflavin A “Aglycone”

Published:2008-11-17 Issue:49 Volume:130 Page:16786-16790
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Wright Benjamin J. D.¹,Hartung John¹,Peng Feng¹,Van de Water Ryan¹,Liu Haibo¹,Tan Quen-Hui¹,Chou Ting-Chao¹,Danishefsky Samuel J.¹

Affiliation:

1. Department of Chemistry, Columbia University, Havemeyer Hall, 3000 Broadway, New York, New York 10027, Laboratory for Bioorganic Chemistry and Preclinical Pharmacology, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, New York 10065

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja805936v

Reference52 articles.

1. Structure of the altromycin B (N7-guanine)-DNA adduct. A proposed prototypic DNA adduct structure for the pluramycin antitumor antibiotics

2. Hedamycin intercalates the DNA helix and, through carbohydrate-mediated recognition in the minor groove, directs N7-alkylation of guanine in the major groove in a sequence-specific manner

3. The interaction of hedamycin and DC92-B in a sequence selective manner with DNA in intact human cells

4. Comparison of the sequence selectivity of the DNA-alkylating pluramycin antitumour antibiotics DC92-B and hedamycin

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