Crystal Structure of the Homo sapiens Kynureninase-3-Hydroxyhippuric Acid Inhibitor Complex: Insights into the Molecular Basis Of Kynureninase Substrate Specificity-Reference-Cited by-同舟云学术

Crystal Structure of the Homo sapiens Kynureninase-3-Hydroxyhippuric Acid Inhibitor Complex: Insights into the Molecular Basis Of Kynureninase Substrate Specificity

Published:2008-12-17 Issue:2 Volume:52 Page:389-396
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lima Santiago¹,Kumar Sunil¹,Gawandi Vijay¹,Momany Cory¹,Phillips Robert S.¹

Affiliation:

1. Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia 30602, Department of Chemistry, University of Georgia, Athens, Georgia 30602, Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, Georgia 30602

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm8010806

Reference45 articles.

1. The Pyridine Ring of NAD Is Formed by a Nonenzymatic Pericyclic Reaction

2. Quinolinic Acid: An Endogenous Metabolite That Produces Axon-Sparing Lesions in Rat Brain

3. Quinolinic acid: A potent endogenous excitant at amino acid receptors in CNS

4. Cerebrospinal Fluid Quinolinic Acid Concentrations are Increased in Acquired Immune Deficiency Syndrome

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