SIRT1 Modulation as a Novel Approach to the Treatment of Diseases of Aging
Author:
Affiliation:
1. Sirtris, A GSK Company, 200 Technology Square, Cambridge, Massachusetts 02139, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm100861p
Reference139 articles.
1. Characterization of Five Human cDNAs with Homology to the Yeast SIR2 Gene: Sir2-like Proteins (Sirtuins) Metabolize NAD and May Have Protein ADP-Ribosyltransferase Activity
2. Phylogenetic Classification of Prokaryotic and Eukaryotic Sir2-like Proteins
3. Recent progress in the biology and physiology of sirtuins
4. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
5. SIRT1 transgenic mice show phenotypes resembling calorie restriction
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