Development of a Practical Synthesis of Stearoyl-CoA Desaturase (SCD1) Inhibitor MK-8245-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Development of a Practical Synthesis of Stearoyl-CoA Desaturase (SCD1) Inhibitor MK-8245

Published:2011-08-23 Issue:5 Volume:15 Page:1073-1080
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Girardin Mélina¹,Dolman Sarah J.¹,Lauzon Sophie¹,Ouellet Stéphane G.¹,Hughes Greg¹,Fernandez Paul²,Zhou George²,O’Shea Paul D.¹

Affiliation:

1. Department of Process Research, Merck Frosst Centre for Therapeutic Research, 16711 Trans Canada Highway, Kirkland, Québec, Canada H9H 3L1

2. Global Science and Technology Commercialization, Merck Sharp and Dohme Corporation, P.O. Box 2000, Rahway, New Jersey 07065, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op200186d

Reference25 articles.

1. Regulation of stearoyl-CoA desaturases and role in metabolism

2. Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase–1

3. Hepatic Stearoyl-CoA Desaturase-1 Deficiency Protects Mice from Carbohydrate-Induced Adiposity and Hepatic Steatosis

4. Thiazole analog as stearoyl-CoA desaturase 1 inhibitor

5. Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438)

Cited by 22 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Electrochemical Cyanation of Alcohols Enabled by an Iodide-Mediated Phosphine P(V/III) Redox Couple;Organic Letters;2024-08-26

2. Iodination–Group-Transfer Reactions to Generate Trisubstituted Iodoalkenes with Regio- and Stereochemical Control;The Journal of Organic Chemistry;2023-09-01

3. Isoxazoles;Comprehensive Heterocyclic Chemistry IV;2022

4. Mitsunobu Reactions in Medicinal Chemistry and Development of Practical Modifications;Methods in Pharmacology and Toxicology;2021-12-14

5. Synthesis and Reactivity of 3‐Halo‐4,5‐dihydroisoxazoles: An Overview;ChemistrySelect;2021-08-23

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3