Development of a Practical and Efficient Synthesis of SIPI-4884, a HMG CoA Reductase Inhibitor for the Treatment of Hypercholesterolemia-Reference-Cited by-同舟云学术

Development of a Practical and Efficient Synthesis of SIPI-4884, a HMG CoA Reductase Inhibitor for the Treatment of Hypercholesterolemia

Published:2013-06-07 Issue:6 Volume:17 Page:921-926
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Hao Qun¹,Pan Jing¹,Li Yongjia¹,Cai Zhengyan¹,Zhou Weicheng¹

Affiliation:

1. State Key Lab of New Drug & Pharmaceutical Process, Shanghai Key Lab of Anti-Infectives, Shanghai Institute of Pharmaceutical Industry, State Institute of Pharmaceutical Industry, Shanghai 200437, China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op400060z

Reference8 articles.

1. The discovery and development of HMG-CoA reductase inhibitors.

2. Synthesis and HMG CoA reductase inhibition of 4-thiophenyl quinolines as potential hypocholesterolemic agents

3. Synthesis and Anti-Hypercholesterolemic Evaluations of Calcium Salts of 4-Substituted Quinoline-Based Mevalonic Acid

4. Synthesis and HMG-CoA reductase inhibition of 2-cyclopropyl-4-thiophenyl-quinoline mevalonolactones

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