Synthesis and Biological Evaluation of Gem-Difluoromethylenated Statin Derivatives as Highly Potent HMG-CoA Reductase Inhibitors-Reference-Cited by-同舟云学术

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Synthesis and Biological Evaluation of Gem-Difluoromethylenated Statin Derivatives as Highly Potent HMG-CoA Reductase Inhibitors

Published:2016-06-15 Issue:8 Volume:34 Page:801-808
ISSN:1001-604X
Container-title:Chinese Journal of Chemistry
language:en
Short-container-title:Chin. J. Chem.

Author:

Zhao Zhao,Cui Jiaxin,Yin Yan,Zhang Heng,Liu Yecheng,Zeng Rui,Fang Chao,Kai Zhenpeng,Wang Zhonghua,Wu Fanhong

Funder

National Natural Science Foundation of China

Shanghai Municipal Education Commission (Plateau Discipline Construction Program)

Publisher

Wiley

Subject

General Chemistry

Reference25 articles.

1. Therapeutic Potential of Mipomersen in the Management of Familial Hypercholesterolaemia

2. Nicotinic acid and derivatives as multifunctional pharmacophores for medical applications

3. Evaluation of short-term safety and efficacy of HMG-CoA reductase inhibitors in hypercholesterolemic patients with elevated serum alanine transaminase concentrations: PITCH study (PITavastatin versus atorvastatin to evaluate the effect on patients with hypercholesterolemia and mild to moderate hepatic damage)

4. Development of an Early Enabling Synthesis for PF-03052334-02: A Novel Hepatoselective HMG-CoA Reductase Inhibitor

5. Association of Cholesteryl Ester Transfer Protein Mass with Peripheral Leukocyte Count Following Statin Therapy

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1. Computer-aided discovery of phenylpyrazole based amides as potent S6K1 inhibitors;RSC Medicinal Chemistry;2020

2. Design, synthesis, and in vitro evaluation of epigoitrin derivatives as neuraminidase inhibitors;Monatshefte für Chemie - Chemical Monthly;2018-08-25

3. Design, Synthesis and Biological Evaluation of Benzothiazoles as Highly Potent ROCK Inhibitors Through Molecular Docking and Free Energy Calculations;CHEM J CHINESE U;2017

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