Discovery of an Imine Reductase for Reductive Amination of Carbonyl Compounds with Sterically Challenging Amines-Reference-Cited by-同舟云学术

Discovery of an Imine Reductase for Reductive Amination of Carbonyl Compounds with Sterically Challenging Amines

Published:2023-01-20 Issue:7 Volume:145 Page:4015-4025
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Chen Fei-Fei¹^ORCID,He Xue-Feng¹,Zhu Xin-Xin¹,Zhang Zhi¹,Shen Xin-Yuan¹,Chen Qi¹,Xu Jian-He¹^ORCID,Turner Nicholas J.²^ORCID,Zheng Gao-Wei¹^ORCID

Affiliation:

1. State Key Laboratory of Bioreactor Engineering, Shanghai Collaborative Innovation Center for Biomanufacturing, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China

2. School of Chemistry, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K.

Funder

Ministry of Science and Technology of the People's Republic of China

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.2c11354

Reference53 articles.

1. Organic synthesis provides opportunities to transform drug discovery

2. Reductive Amination in the Synthesis of Pharmaceuticals

3. Asymmetric Reductive Amination

4. Biocatalytic Approaches to the Synthesis of Enantiomerically Pure Chiral Amines

5. Identification of (S)-selective transaminases for the asymmetric synthesis of bulky chiral amines

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