Hypoxia-Triggered Bioreduction of Poly(<i>N</i>-oxide)–Drug Conjugates Enhances Tumor Penetration and Antitumor Efficacy-Reference-Cited by-同舟云学术

Hypoxia-Triggered Bioreduction of Poly(N-oxide)–Drug Conjugates Enhances Tumor Penetration and Antitumor Efficacy

Published:2023-01-05 Issue:3 Volume:145 Page:1707-1713
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Zhang Longshuai¹²³⁴,Sun Jiawei¹²³⁴⁵,Huang Wenchao²,Zhang Sanke¹²³⁴⁵,Deng Xuliang¹²,Gao Weiping¹²³⁴⁵^ORCID

Affiliation:

1. Department of Geriatric Dentistry, Beijing Laboratory of Biomedical Materials, Peking University School and Hospital of Stomatology, Beijing100081, China

2. Biomedical Engineering Department, Peking University, Beijing100191, China

3. Peking University International Cancer Institute, Beijing100191, China

4. Peking University-Yunnan Baiyao International Medical Research Center, Beijing100191, China

5. Institute of Medical Technology, Health Science Center of Peking University, Beijing100191, China

Funder

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.2c10188

Reference49 articles.

1. Hypoxia in cancer: significance and impact on clinical outcome

2. The hypoxic tumour microenvironment

3. Hypoxic control of metastasis

4. Exploiting tumour hypoxia in cancer treatment

5. Targeting hypoxia in cancer therapy

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