Engineered Living Materials for Advanced Diseases Therapy

Author:

Dong Xue12,Wu Wei2,Pan Pei3,Zhang Xian‐Zheng13ORCID

Affiliation:

1. Institute for Advanced Studies Wuhan University Wuhan 430072 P. R. China

2. Medical Center of Hematology Xinqiao Hospital State Key Laboratory of Trauma Burn and Combined Injury Army Medical University Chongqing 400037 P. R. China

3. Key Laboratory of Biomedical Polymers of Ministry of Education and Department of Chemistry Wuhan University Wuhan 430072 P. R. China

Abstract

AbstractNatural living materials serving as biotherapeutics exhibit great potential for treating various diseases owing to their immunoactivity, tissue targeting, and other biological activities. In this review, the recent developments in engineered living materials, including mammalian cells, bacteria, viruses, fungi, microalgae, plants, and their active derivatives that are used for treating various diseases are summarized. Further, the future perspectives and challenges of such engineered living material‐based biotherapeutics are discussed to provide considerations for future advances in biomedical applications.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Publisher

Wiley

Subject

Mechanical Engineering,Mechanics of Materials,General Materials Science

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