Total Synthesis of Ezetimibe, a Cholesterol Absorption Inhibitor
Author:
Affiliation:
1. Institute of Organic Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo400807c
Reference39 articles.
1. Effectiveness and tolerability of ezetimibe in patients with primary hypercholesterolemia: pooled analysis of two phase II studies
2. Effects of ezetimibe, a new cholesterol absorption inhibitor, on plasma lipids in patients with primary hypercholesterolemia
3. Thiruvengadam, T. K.; Sudhakar, A. R.; Wu, G.InProcess Chemistry in the Pharmaceutical Industry;Gadamasetti, K. G., Ed.Marcel Dekker:New York, 1999; pp221–242and references therein.
4. Discovery of 1-(4-Fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)- hydroxypropyl]-(4S)-(4-hydroxyphenyl)-2-azetidinone (SCH 58235): A Designed, Potent, Orally Active Inhibitor of Cholesterol Absorption
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