Design, Synthesis, and Pharmacological Characterization of Indol-3-ylacetamides, Indol-3-yloxoacetamides, and Indol-3-ylcarboxamides: Potent and Selective CB2 Cannabinoid Receptor Inverse Agonists-Reference-Cited by-同舟云学术

Design, Synthesis, and Pharmacological Characterization of Indol-3-ylacetamides, Indol-3-yloxoacetamides, and Indol-3-ylcarboxamides: Potent and Selective CB2 Cannabinoid Receptor Inverse Agonists

Published:2012-05-16 Issue:11 Volume:55 Page:5391-5402
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pasquini Serena¹,Mugnaini Claudia¹,Ligresti Alessia²,Tafi Andrea¹,Brogi Simone¹,Falciani Chiara¹,Pedani Valentina¹,Pesco Nicolò¹,Guida Francesca³,Luongo Livio³,Varani Katia⁴,Borea Pier Andrea⁴,Maione Sabatino³,Di Marzo Vincenzo²,Corelli Federico¹

Affiliation:

1. Dipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena, Via A. Moro, 53100 Siena, Italy

2. Endocannabinoid Research Group, Istituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, Via dei Campi Flegrei 34, 80078 Pozzuoli (Napoli), Italy

3. Endocannabinoid Research Group, Dipartimento di Medicina Sperimentale − Sezione di Farmacologia “ Donatelli”, Seconda Università di Napoli, Via S. Maria di Costantinopoli 16, 80138 Napoli, Italy

4. Dipartimento di Medicina Clinica e Sperimentale, Sezione di Farmacologia, Università degli Studi di Ferrara, Via Fossato di Mortara 17-19, 44121 Ferrara, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm3003334

Reference71 articles.

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5. Identification and Functional Characterization of Brainstem Cannabinoid CB 2 Receptors

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