Use of Acetylcholine Binding Protein in the Search for Novel α7 Nicotinic Receptor Ligands. In Silico Docking, Pharmacological Screening, and X-ray Analysis-Reference-Cited by-同舟云学术

Use of Acetylcholine Binding Protein in the Search for Novel α7 Nicotinic Receptor Ligands. In Silico Docking, Pharmacological Screening, and X-ray Analysis

Published:2009-03-30 Issue:8 Volume:52 Page:2372-2383
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ulens Chris¹,Akdemir Atilla¹,Jongejan Aldo¹,van Elk Rene¹,Bertrand Sonia¹,Perrakis Anastassis¹,Leurs Rob¹,Smit August B.¹,Sixma Titia K.¹,Bertrand Daniel¹,de Esch Iwan J. P.¹

Affiliation:

1. Division of Molecular Carcinogenesis, Netherlands Cancer Institute, Amsterdam, The Netherlands, Leiden/Amsterdam Center for Drug Research (LACDR), Division of Medicinal Chemistry, Faculty of Sciences, VU University Amsterdam, Amsterdam, The Netherlands, Department of Molecular and Cellular Neurobiology, Institute of Neurosciences, Faculty of Earth and Life Sciences, VU University Amsterdam, Amsterdam, The Netherlands, and Department of Neuroscience, Centre Medical Universitaire, Geneva, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm801400g

Reference47 articles.

1. Neuronal Nicotinic Acetylcholine Receptors: Structural Revelations, Target Identifications, and Therapeutic Inspirations

2. The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation

3. Nicotinic receptor agonists as neuroprotective/neurotrophic drugs. Progress in molecular mechanisms

4. Varenicline

5. A glia-derived acetylcholine-binding protein that modulates synaptic transmission

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