1. Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland, Callerio Foundation Onlus, Via A. Fleming 22-31, 34127, Trieste, Italy, and Dipartimento di Scienze Biomediche, Università di Trieste, Via L. Giorgieri 7, 34127, Trieste, Italy