Ligand-Based Models for the Isoform Specificity of Cytochrome P450 3A4, 2D6, and 2C9 Substrates-Reference-Cited by-同舟云学术

Ligand-Based Models for the Isoform Specificity of Cytochrome P450 3A4, 2D6, and 2C9 Substrates

Published:2007-07-01 Issue:4 Volume:47 Page:1688-1701
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Terfloth Lothar¹,Bienfait Bruno¹,Gasteiger Johann¹

Affiliation:

1. Computer-Chemie-Centrum and Institut für Organische Chemie, Universität Erlangen-Nürnberg, Nägelsbachstrasse 25, D-91052, Erlangen, Germany, and Molecular Networks GmbH, Henkestrasse 91, D-91052 Erlangen, Germany

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ci700010t

Reference54 articles.

1. Structure-Based Methods for the Prediction of the Dominant P450 Enzyme in Human Drug Biotransformation: Consideration of CYP3A4, CYP2C9, CYP2D6

2. Computational approaches for predicting CYP-related metabolism properties in the screening of new drugs

Cited by 84 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Unlocking The Mysteries of DNA Adducts with Artificial Intelligence;ChemBioChem;2023-11-13

2. Alternative Methods for Pulmonary-Administered Drugs Metabolism: A Breath of Change;Mini-Reviews in Medicinal Chemistry;2023-02

3. Biotransformations in Drug Metabolism;Drug Metabolism Handbook;2022-11-18

4. BioTransformer 3.0—a web server for accurately predicting metabolic transformation products;Nucleic Acids Research;2022-05-10

5. The FDA-Approved Drug Cobicistat Synergizes with Remdesivir To Inhibit SARS-CoV-2 Replication In Vitro and Decreases Viral Titers and Disease Progression in Syrian Hamsters;mBio;2022-04-26