Simultaneous Evaluation of a Vaccine Component Microheterogeneity and Conformational Integrity Using Native Mass Spectrometry and Limited Charge Reduction-Reference-Cited by-同舟云学术

Simultaneous Evaluation of a Vaccine Component Microheterogeneity and Conformational Integrity Using Native Mass Spectrometry and Limited Charge Reduction

Published:2021-05-19 Issue:7 Volume:32 Page:1631-1637
ISSN:1044-0305
Container-title:Journal of the American Society for Mass Spectrometry
language:en
Short-container-title:J. Am. Soc. Mass Spectrom.

Author:

Bobst Cedric E.¹,Sperry Justin²,Friese Olga V.²,Kaltashov Igor A.¹^ORCID

Affiliation:

1. Department of Chemistry, University of Massachusetts-Amherst, Amherst, Massachusetts 01003, United States;

2. BioTherapeutics Pharmaceutical Sciences, Pfizer, St. Louis, Missouri 63017, United States

Funder

Division of Chemistry

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Spectroscopy,Structural Biology

Link

https://pubs.acs.org/doi/pdf/10.1021/jasms.1c00091

Reference26 articles.

1. Mass Spectrometric Strategies and Their Applications for Molecular Mass Determination of Recombinant Therapeutic Proteins

2. Advances and challenges in analytical characterization of biotechnology products: Mass spectrometry-based approaches to study properties and behavior of protein therapeutics

3. Mass spectrometry for the biophysical characterization of therapeutic monoclonal antibodies

4. Safety and immunogenicity of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine in two formulations: two open, non-randomised phase 1/2 studies from Russia

5. Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

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