Synthesis of 1-Boc-3-fluoroazetidine-3-carboxylic Acid

Author:

Van Hende Eva1,Verniest Guido1,Deroose Frederik1,Thuring Jan-Willem1,Macdonald Gregor1,De Kimpe Norbert1

Affiliation:

1. Department of Organic Chemistry, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium, and Johnson & Johnson Pharmaceutical Research & Development, a Division of Janssen Pharmaceutica NV, Turnhoutseweg 30, B-2340 Beerse, Belgium

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Reference33 articles.

1. aPapeo, G. M. E.; Caronni, D.; Dalvit, C.; Giordano, P.; Mongelli, N.; Veronesi, M.; Ciprandi, F.Eur. Pat. Appl. EP 1923398 A1 20080521, 2008.

2. bGrabstein, K. H.; Wang, A.; Nairn, N.; Winblade, G.; Thomas, J.U.S. Pat. Appl. Publ. US 2008096819 A1 20080424, 2008.

3. (2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]triazolo[1,5-a]- pyridin-6-ylphenyl)butanamide:  A Selective α-Amino Amide Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes

4. dCelanire, S.; Quere, L.; Denonne, F.; Provins, L.PCT Int. Appl. WO 2007048595 A1 20070503, 2007.

5. Dual serotonin transporter/histamine H3 ligands: Optimization of the H3 pharmacophore

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