Effect of Intestinal Glucuronidation in Limiting Hepatic Exposure and Bioactivation of Raloxifene in Humans and Rats
Author:
Affiliation:
1. Pharmacokinetics, Dynamics and Metabolism, Pfizer Global Research and Development, San Diego, California 92121, and Groton, Connecticut 06340
Publisher
American Chemical Society (ACS)
Subject
Toxicology,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/tx800323w
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4. Cytochrome P450 3A4-Mediated Bioactivation of Raloxifene: Irreversible Enzyme Inhibition and Thiol Adduct Formation
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